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Cisplatin, used in chemotherapy, and aristolochic acid, widely diffused in the Chinese herbal medicine, known to induce nephrotoxic effect, were perfused and the OPTEC-on-chip revealed to be a more reliable in vitro system compared to PTEC ( Figure 4M )

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2008, [ Pre-publication history The pre-publication history for this paper can be accessed here: Acknowledgements This bioequivalence study was conducted at AAIPharma, Neu-Ulm Germany

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