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Decrease in adiponectin levels by genetic and environmental factors contributes to the development of the metabolic syndrome

doi:10.1016/j.heares.2015.06.005 70
Furthermore, curcumin augments the effectiveness of Doxorubicin and Paclitaxel in overcoming MDR in lung cancer (A549), ovarian cancer (SK-OV-3), and colon cancer (HCT-8) cells by inhibiting both the protein function and expression of P-gp [307, 308]

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h , Doseresponse curves for control (sgCtrl) and CRBN KO (sgCRBN) HCT116 cells treated with SMART1 or SMART1Et for 72 h (4 independent experiments)

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