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First, current inhibitors such as GsMTx4 are nonspecific inhibitors that may adversely affect Piezo1 expression in normal tissues, increasing the risk of treatment side effects

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Corticosteroid medications, such as dexamethasone, also significantly decrease MAOA activity.[ref] A sudden suppression of MAO-A could increase dopamine and other neurotransmitter levels, sharpening awareness and quick decision-making, which makes sense in a situation that is suddenly stressful

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