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83 The 2020 ACR guideline recommends genetic testing for the HLA-B*5801 allele before starting allopurinol for patients who are African Americans or of Southeast Asian descent

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Postmortem and imaging studies have revealed electron transport chain defects and impaired pyruvate dehydrogenase activity in ASD brains, with regional reductions in Complex I availability and non-ETC enzymes such as aconitase and PDH

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While heart palpitations can be uncomfortable and even frightening, they are not always an indication of a serious medical issue