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The latter in response to stimulation by intestinal microbial antigens, particularly LPS, upregulate the production of proinflammatory cytokines (e.g., IL-1, IL-6, TNF) and reactive oxygen species (ROS), contributing to the enhancement of pro-inflammatory reactions (Van Spaendonk et al., 2017)
n = 5), and IGF-1 plus L2-Cmu ( n = 5 for lung and n = 6 for heart)
Oxidative stress can cause insulin resistance and episodes of hypoglycemia
Schiffman et al, 2023)
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