labial melanotic macule skin cancer freckle on lip Does anyone know what this black mark my is? Started last August so it's I've had it nearly a year, was living in Spain at the time for 6 months Oral melanotic macules are harmless
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doi: 10.3389/fnbeh.2015.00358 Received 10 June 2015 Accepted 09 December 2015 Published 24 December 2015 Volume 9 - 2015 Edited by James P
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It could also trigger various changes, such as modification of amino-acid side chains, peptide scission, structural unfolding, and protein depolymerization (78)

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No freezing reconstituted peptides causes ice crystal formation that physically disrupts peptide structure, leading to irreversible aggregation and loss of biological activity