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Similarly, sleep deprivation can impair the balance between the appetitesuppressing hormone leptin and the hungerstimulating hormone ghrelin, causing the brain to receive a false energy deficit signal, thereby intensifying hunger and cravings and ultimately leading to weight gain [38]

The selective glucocorticoid receptor modulator cort 113176 reduces neurodegeneration and neuroinflammation in wobbler mice spinal cord

Its multifaceted approach, including appetite suppression and slowed gastric emptying, has been shown to result in significant reductions in body fat

Studies have shown that human (Schrenk-Siemens et al., 2015), zebrafish (Faucherre et al., 2013), chicken (Soattin et al., 2016), Drosophila (He et al., 2018) bird (Schneider et al., 2014), mouse (Ikeda et al., 2014