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Description
These genes are closely associated with mutations in the copper metabolism-related diseases Menkes disease and Wilsons disease, respectively ( A shared mechanism underlies both copper-induced cell death and dysregulation of copper homeostasis

This view, however, has been challenged by recent reports, which found that some neutrophils can survive this event and remain structurally intact, suggesting two mechanisms of NETosis: suicidal and vital [125, 131]

Variations in the COX-2 gene can be implicated in oxidative stress-related conditions such as cancer, cardiovascular diseases, and neurodegenerative disorders

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BDNF is a polyfunctional neurotrophin, like nerve growth factor (NGF) or neurotrophin-3 (NT-3), and has firmly established itself, after its initial discovery by Yves-Alain Barde et al

As one of the body's most important naturally occurring antioxidants, glutathione is widely used in dietary supplements, functional foods, beauty-from-within products, anti-aging formulations, and skincare applications
