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The lyophilised blend should be stored at 20C and protected from moisture and light

Wang H, Li L, Qin LL et al (2018) Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency

Unlike others, the absorption of vitamin B12 depends on a protein called intrinsic factor, which is produced in the stomach

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Because of its defined molecular profile, the compound is frequently used in laboratory studies examining metabolic regulation and biochemical processes

So supplements shouldnt provide negative side effects