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Leveraging the replication stress response to optimize cancer therapy

Kovacs-Nolan et al

Mechanism of oxidative stress in IBD While the precise mechanisms responsible for the development of IBD remain unclear, it is widely accepted that multiple factors contribute to its etiology, including overproduction of ROS, damage to biomolecules, mitochondrial dysfunction, recruitment of immune cells, impaired antioxidant defense system, and the activation of inflammatory pathways ( Figure 1 )

Retrieved 6 September 2015

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Exploring the aggregation-prone core of human Cystatin C: a structural study