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Additional mass spectrometry settings were as follows: ion spray voltage, 3.0 kV

This isoform was specifically enhanced in activated myofibroblasts in vitro upon angiotensin II and TGF-1 stimulation and in vivo in mouse, rat, and human fibrotic hearts 88

In contrast, metformin could suppress the expression of HSD and aromatase (P450 arom) in uterine fibroid cells and reduce estrogen synthesis, thereby inhibiting the growth of fibroids (Wang et al., 2019)

[DOI] [PMC free article] [PubMed] [Google Scholar] 125.Jackson J.G., Zhang X., Yoneda T., Yee D

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