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In humans contradictory observations still exist, since some lines of evidence suggest that supplementation of the diet with fish oils results in a reduced production of IL-1, IL-6, TNF-, and IL-2 [190], and an alteration of gene expression profiles to a more antiinflammatory and antiatherogenic status in peripheral blood mononuclear cells in vitro [191]

Houjeghani S, et al

Ethanolamine and phosphoethanolamine inhibit mitochondrial function in vitro: implications for mitochondrial dysfunction hypothesis in depression and bipolar disorder

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Healthcare providers are encouraged to assess the patients psychological state and consider recommending psychosexual counseling, such as CBT or sensate focus exercises, alongside pharmacological treatments