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Hormonal fluctuations are another key consideration: Rapid weight loss can significantly alter SHBG and free testosterone levels, potentially leading to symptoms of androgen excess or deficiency even when the prescribed testosterone dose remains unchanged

Diagn Pathol (2010) 5:79

[23] On the other hand, certain drugs like isoniazid, hydralazine, and some penicillamine can cause vitamin B deficiency and might necessitate concurrent pyridoxine supplementation

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Dietary Restriction for The Treatment of Meniere's Disease