glp-1 receptor agonist mechanism of action Frontiers List of GLP-1 Receptor Agonists
Description
Glucagon promotes satiety and increases energy expenditure in humans
Bariatric surgery was associated with greater weight loss, but GLP-1 RA therapy was associated with better outcomes
The long-acting compounds have insulinotropic and glucagonostatic actions, and exert their main effect on fasting glucose levels [27-29]
Mahalingam S, Bellamkonda R, Arumugam MK, Perumal SK, Yoon J, Casey C, et al
doi: 10.1038/nature05485
doi: 10.1038/bjp.2008.100 97 WebsterLRReisfieldGMDasguptaN
