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doi: 10.1002/ptr.v38.9 15 JinEJJoYWeiSRizzoMRyuDGarianiK

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These findings suggest that GABA and its metabolite levels and ratios may serve as potential targets for the clinical diagnosis and treatment of ASD ( 4.3 Comorbidities related to ASD Disruption of the GABAergic system is a core pathological mechanism underlying various ASD syndromes, such as FXS, Rett syndrome, and Dup15q, manifesting as E/I imbalance, abnormal gene expression, and defects in interneuron development

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