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On the other hand, the excessive activation of Nrf2/HO-1 disrupts the balance of iron ion metabolism, leading to ferroptosis [288, 289]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 137.Yang R, Feng J, Wan H, Zeng X, Ji P, Zhang J, Liver injury associated with the severity of COVID-19: A meta-analysis

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It acts locally in the colon, minimizing the risks often seen with traditional drugs

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doi: 10.1111/raq.12869 44 ManzoorZ.SajadA.QadiriS

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