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As healing begins, inflammation fades

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Dilated blood vessels offer less resistance to blood flow, and reduced resistance means lower pressure for any given cardiac output

Oral pills, conversely, must navigate the digestive system, resulting in significantly lower absorption rates (estimated at 1-2%)

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73 IL-6 activates neutrophils, causing neutrophil infiltration at the inflammatory sites, inducing neutrophils to release elastase and various oxygen free radicals, destroying alveolar surfactants, increasing pulmonary vascular permeability and inducing pulmonary oedema
