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Description
Although initial clinical assessment pointed toward a potential hematologic malignancy, comprehensive testing, including SPEP, reticulocyte count/fraction, serum folate, and serum vitamin B12, revealed only severe vitamin B12 deficiency, with a level of less than 150, with the presence of IF antibodies

10.1038/ng1098 14

When CMI falls below a critical threshold, as it can in older and immunocompromised persons, VZV can reactivate, causing shingles and, occasionally, postherpetic neuralgia (PHN) and other complications

Cell 166 , 7787 (2016)

[6] Scientists working with test models also comment that IGF-1 may have a GH independent growth stimulating effect, which with respect to cartilage cells is possibly optimized by the synergistic action with GH

Scores range from 1 to 7, with 5 indicating markedly ill
