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doi: 10.1016/j.clim.2013.08.008

There is no good evidence that B12 injections accelerate fat loss in people with normal B12 levels

The finding that 12 weeks showed a larger effect size (SMD: 1.08) than 2124 weeks (SMD: 0.64) does not mean treatment becomes ineffective after 12 weeks
It is a short phase, lasting only a few weeks

however, in subsequent years there are no conversion costs

It stimulates insulin release in a glucose-dependent manner, suppresses glucagon, slows gastric emptying, and signals satiety to the brain
