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It reduced ionized calcium-binding adaptor molecule 1-stimulated microglia and pro-inflammatory mediator levels, alleviating both motor and non-motor impairments in Parkinson's disease (Kim et al., 2019)

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PMID: 23075564

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doi: 10.1186/gb-2002-3-7-research0034 20 HellemansJMortierGde PaepeASpelemanFVandesompeleJ

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ObirikorangCLokpoSYOwireduWKBAAhenkorah-FondjoLOsei-YeboahJDueduKOet al

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MECHANISM OF LOCAL ANESTHETIC TOXICITY Local anesthetics are generally safe and effective when limited to the site of therapy, such as tissue infiltration, near a nerve or a plexus of nerves

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We also investigated the effects of L-theanine on nicotinic receptors binding and function

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