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In the new Proceedings of the National Academy of Sciences paper, researchers reveal people with depression have lower levels of ALC in their blood
We next examined acyl-CoA abundance, finding that acetyl-CoA is modestly reduced, HMG-CoA is dramatically reduced, and malonyl-CoA tends to be elevated in DKO cells, similar to the phenotype seen in ACLY KO cells in the absence of acetate (Figure 2C
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