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After 4 and 8 weeks, respectively, the experimental group core muscle strength and stability had significantly improved

mRS: Modified Rankin Scale

A reasonable discontinuation protocol involves reducing dose by one tier every 4 to 6 weeks while intensifying dietary control and physical activity

While effective for mild pigmentation, some reviewers found it less impactful for severe hereditary dark circles

J Biol Chem 1991;266:1932833
