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Iron, as a co-factor of TH, increases TH activity and upregulates DA levels, while this is not seen with other divalent metal ions [109, 110]

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Among all the complexes, promising in vitro antitumor activity was found for Pt(IV) complexes based on the cisplatin scaffold, bearing one axial indole carboxylate and one axial hydroxido ligand ( 1A and 1P )