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Ustekinumab has significant effect on moderate and severe psoriasis

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Mitochondria and post mitochondrial (PMS) fractions were prepared by centrifugation and the purity of the isolated fractions was checked for cross contamination as described before [23]

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GSH exhibits multiple antioxidant actions, involving direct conjugation with free radicals such as ROS and reactive nitrogen species 46 and enzyme-mediated neutralization of free radicals, including GSH peroxidase (GPx), which detoxifies peroxides with GSH acting as an electron donor 47
