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It has been shown that SARS-CoV-1 N protein interacts with the host transcriptional factor NF-B in a dose-dependent manner to regulate IL-6 expression [55,56]
67 A moderate increase in ROS levels may increase CDK2 activity, which is vital for bypassing senescence and enabling cancer cell immortalization
The GPX4 pathway is the most well-known defense against ferroptosis
doi: 10.1016/S0003-9861(53)80001-9
Recombinant GST-p40PX was also purchased (Echelon Biosciences
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