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mechanism not fully characterized

Similar to the in vitro hMOR binding and functional studies, mitragynine also exhibited the weakest antinociceptive effect (E max 17.3%) among the tested alkaloids at the highest dose tested (10 mg/kg, i.v.)

Marketing claims about synergy remain speculative without human evidence

DNA was extracted by salting out method from peripheral blood and multiplex polymerase chain reaction was performed following agarose gel electrophoresis to detect gstt1 and gstm1 null genotypes

Although there are various modes of cell death, we believe that different forms of cell death may share similarities and be closely connected, contributing to the outcome through their integrated effects

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