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In terms of selecting the formulation delivery device, in a human study with a whole-virus influenza liquid vaccine without adjuvant, the immune response was better when using the breath-powered Bi-Directional OptiNose device and nasal drops in the delivery, rather than traditional nasal spray and an oral spray [22]

The SARS coronavirus nucleocapsid proteinforms and functions

However, the latest study provides a novel idea for the mechanism of TMAO promoting thrombosis, i.e., an increase in TMAO results in promotion of tissue factor (TF) expression in the vascular endothelium