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Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis

Cancer Cell 17 , 98110 (2010)

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This can result in cell membrane damage, DNA mutations and fibrosis
Goss AM, Chandler-Laney PC, Ovalle F, Goree LL, Azziz R, Desmond RA, Bates GW, Gower BA

Among these, selenium-dependent glutathione peroxidase 4 (GPX4) is crucial for preventing ferroptosis by detoxifying phospholipid hydroperoxide into the corresponding phospholipid alcohol at the expense of glutathione (GSH) [12,13,14,15]