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Description
SAM originated from methionine cycle in which 5-methyl THF transfers methyl groups to homocysteine in a reaction catalyzed by methionine synthase to produce methionine
Zhang X, Li W, Ma Y, Zhao X, He L, Sun P, Wang H


doi: 10.1016/S1474-4422(11)70261-7 85 Gil-BeaF

At the genomic level, Epitalon modulated the expression of key circadian rhythm genes: Clock expression in leukocytes decreased 1.8-fold, Cry2 expression doubled, and Csnk1e expression in lymphocytes decreased by 2.1-fold, all with statistical significance

Huntingtons disease: the challenge for cell biologists