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Since several compounds that disrupt p53-Mdm2 binding are now being tested in the clinic, these results may have profound implications for the future clinical use of both APR-246 and inhibitors of p53-Mdm2 binding

Marine-derived nutritional interventions, particularly those rich in long-chain omega- 3/omega- 6 LC-PUFAs, exhibit anti-adipogenic properties through leptin signaling interference

"Four things a doctor who's written best-selling books about aging does daily in the hope of living longer"

4H1) showed substantially improved search efficiency, demonstrating trajectories resembling control patterns with reduced circling behavior and more targeted platform approaches

Stobiecka, M., Krl, J., & Brodziak, A

doi: 10.1038/s41392-022-00887-2 118 ZhangX.ShiL.SunT.GuoK.GengS