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These cells are essential in fighting off infections and keeping your immune system in good working order

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Moreover, systemic comorbidities highly relevant to human periodontitis, such as diabetes, obesity, smoking, or agerelated immune senescence, are absent from most standard models despite their known effects on inflammatory networks, bone metabolism, and treatment outcomes [102]

The ability to detect these changes early may aid in the diagnosis and monitoring of PDAC, offering a critical advantage as pancreatic cancers are known for their late presentation
