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Such episodes were reported in 4.1%, 7.3%, and 5.7% in the placebo, 25 mg and 50 mg methylcobalamin groups, respectively

Neuronal mitochondria are the target of glutamate, which attenuates succinate dehydrogenase (a key enzyme of the TCA cycle) inhibition by oxaloacetate [63], with further induction of ROS production [64]

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