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It was found that the toxic effect of sorafenib on hepatocellular carcinoma cells was partly dependent on ferroptosis rather than apoptosis, and this toxic effect was also not dependent on its multikinase inhibitory activity, but induced ferroptosis by inducing iron aggregation and lipid peroxidation stress in hepatocellular carcinoma cells, and that depletion of stored iron in hepatocellular carcinoma cells by use of iron chelating agents could effectively weaken the cytotoxic effect of sorafenib

Every prenatal IV therapy schedule must be supervised by a qualified healthcare provider who can monitor maternal hydration, electrolyte balance, and fetal health simultaneously

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[DOI] [PMC free article] [PubMed] [Google Scholar] [33].Avdeev SN, Gaynitdinova VV, Merzhoeva ZM, Berikkhanov ZGM

The members have been renamed for convenience as OsDJ-1A (LOC_Os01g11860), OsDJ-1B (LOC_Os01g11880), OsDJ-1C (LOC_Os04g57590), OsDJ-1D (LOC_Os05g44330), OsDJ-1E (LOC_Os06g34040) and OsDJ-1F (LOC_Os11g37920)