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This might be especially true given their proposed involvement in submucosal gland secretion [201], muc5AC expression [207], inflammation [210], bronchoconstriction [211], and lung injury repair [212]

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These large quantities of thyroid hormones increase the bodys metabolism function which causes several symptoms such as rapid or irregular heartbeat, insomnia, increased body temperature, irritability, shakiness, and unintentional weight loss

Unlike pharmaceutical agents (e.g., statins) that carry side effects (e.g., myopathy), probiotics are generally safe and exert pleiotropic effects, including cholesterol lowering, anti-inflammation, and endothelial protection ( 2 PRISMA compliance and literature selection process 3 Gut microbiota dysbiosis and atherosclerosis: the mechanistic link Gut microbiota dysbiosis contributes to AS through three interconnected pathways: metabolic dysregulation, inflammatory activation, and vascular dysfunction ( Figure 1 )

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