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J Alzheimers Dis JAD

Malyla et al., 2023), breast cancer (Wellenstein et al., 2019), and colorectal cancer (Morin et al., 1997), while also contributing to the pathogenesis of non-cancer diseases, including chronic obstructive pulmonary disease (Skronska-Wasek et al., 2017) and atherosclerosis ( In lung cancer, -catenin is a key molecule governing tumor growth and EMT

Condensin is required for nonhistone protein assembly and structural integrity of vertebrate mitotic chromosomes

The disease usually worsens rapidly and most people with PSP develop severe disability within three to five years of symptom onset

While glia heavily influence neuronal functions and the propagation of signals along neural tracts, they can also be considered an independent functional and regulatory matrix of the CNS, since they can function independently of neuronal nuclei und clusters, as well as receive input from all the major neurotransmitter systems

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