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The typical IM sites are the deltoid muscle (upper arm) or the gluteal muscle (buttock)
The multi-faceted basis of vitamin B12 (cobalamin) neurotrophism in adult central nervous system: Lessons learned from its deficiency

Selecting the right treatment depends on several factors, including symptom severity, how long symptoms have persisted, and how the condition affects your daily activities

They are typically administered intramuscularly (into the muscle)

However, a very small percentage of B12 from a supplemental dose is absorbed by passive diffusion, rather than by intrinsic factor, such that vegans can make up for taking B12 only once per day, or even only once per week, by taking larger doses than normally provided by food
