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For instance, transplantation of gut microbiota from AUD patients into mice induced a decrease in BHBA metabolism that may be associated with social impairment and depression in AUD (221)

Importantly, BPC-157 shows no direct angiogenic effect on endothelial cell cultures, suggesting its pro-angiogenic activity requires the context of injury and healing responses present in vivoa safety feature that may limit unwanted neovascularization in healthy tissues

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doi: 10.1016/j.chemosphere.2019.125747, 17 HoweC

Also, recent evidence shows that the use of nanocarrier-based phytochemical delivery can increase the capacity of phytochemicals to regulate non-coding RNAs and epigenetic pathways in cancer stem cells, which translational opportunities in the next-generation therapies [79]