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Conclusions and Future Perspectives Since the beginning of plant GST research in 1970 the fundamental questions have remained largely unanswered: what are the physiological roles of GST isoenzymes and which metabolites are the natural, endogenous substrates of GSTs

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Furthermore, clinical findings from a study involving 81 NSCLC patients treated solely with ICIs showed that those with MET amplification exhibited ICI resistance and had suboptimal PFS [123]

Cao J, Chen TM, Hao WJ, et al