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HIF-1 promotes the conversion of pyruvate to lactate and, in synergy with pyruvate dehydrogenase kinase (PDHK), inhibits the transformation of lactate to acetyl-CoA (167, 168)

Transient receptor potential melastatin 2 (TRPM2) inhibition by antioxidant, N-Acetyl-l-Cysteine, reduces global cerebral ischemia-induced neuronal death

SchoenfeldJSibenallerZMapuskarKWagnerBCramer-MoralesKFurqanMet alO2 - and H2O2-mediated disruption of fe metabolism causes the differential susceptibility of NSCLC and GBM to pharmacological ascorbate

A full course often means multiple sessions over several weeks or months

Neuroinflammation is a critical pathological phenotype of AD, and many studies indicate that NLRP3 and TNF- play great roles in neuroinflammation of AD pathology [36, 37]

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