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These agents normally bind the glutamate receptor and the complex is transported across the cell resulting in reduced concentrations, hence attenuating effects of these drugs

Altered peripheral blood compounds in drug-nave first-episode patients with either schizophrenia or major depressive disorder: a meta-analysis

[DOI] [PubMed] [Google Scholar] 174.Vicente S

Therefore Met generally retains a reduced state in the extracellular environment [107]

Q.WangQ.TaoX.LiJ.ZhangS.et al (2020)
