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Description
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Intervention strategies targeting fatty acid metabolism (such as PPAR agonists and CD36 inhibitors) are still in the experimental stage and face challenges, including the complexity of target pathways, off-target toxicity of drugs, and individual differences in responses
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Demonstrated proof-of-concept for the dual agonist approach Phase 1b/2a (SC): Up to 24% weight loss at 36 weeks with doses up to 60 mg
