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These channels were also identified in cerebellum, dorsal root ganglia, trigeminal and nodose vagal that give rise to afferent nerve fibre bundles that transduce different sensory signals (mechanical, chemical, thermal)
In Helicobacter pylori -driven gastric carcinogenesis, infection sharply upregulates CHAC1

Roveri A
Grslund S, et al

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Their studies exploring ROS production inside the cells are strongly involved in insulin resistance in hyperglycemic conditions
