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Methods We used molecular modelling to develop a series of rationally designed peptides to mimic and target FOXO4 disrupting the FOXO4-TP53 interaction and releasing TP53 to induce apoptosis

Evelyne Bischof, who runs a healthy longevity medicine practice in Shanghai and Tel Aviv, said she is not "radically against" peptide use, but her patients only use FDA-approved peptides like Ozempic, "and only from very reliable providers." She has concerns about unauthorized peptides causing allergic reactions, or including extra substances that aren't listed on the label, like steroids