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Programmed death of Microglia in Alzheimers Disease: Autophagy, Ferroptosis, and Pyroptosis
Parkin-mediated polyubiquitination then facilitates the interaction with autophagy receptors, ultimately leading to autophagosome formation and lysosomal degradation of dysfunctional mitochondria
However, a subsequent study indicated that CBS and CSE catalyze the transformation of cystine to CysSSH, which interacts with GSH, thus forming GSSH and H 2 S based on an equilibrium reaction among them 17
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