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Beyond the observed increase in periosteal thickness and trabecular areas, there was a marked elevation in vital growth factors and proteins, such as VEGF, -catenin, and TGF-, in the ozone-administered group versus the control [41]

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Xiao et al

622 In another study focusing on ocular neovascularization, a contributory factor to blindness, MT1/2 was found to play significant roles in retinal and choroidal neovascularization

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Notably, FGF-21 can cross the BBB, directly impacting neuronal and glial function [92]
