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This surgical intervention involves the removal of excess skin and fat from the abdominal area, resulting in a flatter and more toned appearance

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Since FGF21 represents one of the most susceptible targets of ATF4, with three amino acid response elements (AARE) in its promoter region (Maruyama et al, 2016), we also found that upstream induction of ATF4 expression (Appendix Fig

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Because glutamine is the source of -KG, glutaminase inhibitors such as BPTES interfere with -KG homeostasis and lead to inhibited proliferation in cancer cells carrying this mutant IDH1 (Seltzer et al., 2010)