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High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells

Glutathione is a key player in these pathways, but adding more doesn't strictly equate to better detoxification if your system isn't under specific stress

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These symptoms occur because alcohol acts as a diuretic, causing dehydration while your liver struggles to process acetaldehyde, a toxic byproduct of alcohol metabolism

This means that histamine from food that causes irritation is eliminated more quickly and a flood of histamine is counteracted

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