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AE-M: Formal Analysis, Investigation, Project administration, Software, Validation, Writing original draft, Writing review and editing

One is a hormonally active, FDA-approved metabolic drug with robust human evidence

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However, the available human research is limited, and controlled clinical trials have not demonstrated consistent or substantial benefits

Over the years, research has suggested that certain nutritional deficiencies, particularly Vitamin B12 and folic acid, might play a role in the onset or progression of vitiligo