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Additionally, with the maximal clinical effect of timolol on increased intraocular pressure, minimal bounding to beta receptors occurred [67]

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Materials and methods Cell culturing RWPE-1 (ATCC CRL-11609) epithelial cells and DU-145 (ATCC HTB-81) human prostate carcinoma cells were purchased from American Type Culture Collection (Manassas, Virginia, USA)

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