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Because of the absence of a nucleus and mitochondria, the red cell is incapable of generating energy via the (oxidative) Krebs cycle and depends mainly on the anaerobic conversion of glucose by the Embden-Meyerhof pathway (EMP, or direct glycolytic pathway) and the oxidative hexose monophosphate pathway (HMP, or pentose phosphate shunt) (Figure 23-1)
Discovered in 2015 by researcher Changhan David Lee and colleagues at the University of Southern California, MOTS-c sits at the intersection of some of the most active areas in longevity science: mitochondrial biology, insulin sensitivity, skeletal muscle metabolism, and the molecular response to exercise
What matters most is who administers the treatment and what formulas are used
Sakaue S, Kasai T, Mizuta I, Suematsu M, Osone S, Azuma Y, et al
